Hot flushes, Night sweats, Depression, Cold hands & Feet, Loss of libido, Irritable, Vaginal dryness, Weight Gain
A comprehensive menopausal profile. Although menopause is a normal part of a woman’s maturation, many experience discomfort including hot flushes, night seats, cold hands and feet, depression, loss of libido, irritation and vaginal dryness. The measurement of oestradiol and progesterone from a single saliva sample can give valuable information about the balance of these hormones.
This profiles also evaluates adrenal cortex function and the circadian fluctuation in the hormones, cortisol and DHEA. An inappropriate adrenal response can negatively impact on many other common health complaints, including menopause. The other hormones that can influence menopausal symptoms are also measured, including testosterone and melatonin.
Salivary testing of these hormones, unlike serum testing, measures the free, un-bound fraction of hormone that is available to exert its effect on the target tissue. In addition, levels of anti- and pro- carcinogenic oestrogen metabolites (2 and 16 alpha-hydroxy derivatives of oestrone and oestradiol) which can help assess if there is an increased oestrogen-sensitive cancer risk.
Tests included: Adrenal Stress Profile, Melatonin Profile, Testosterone, Oestrogen Metabolism Assessment, 1-Day Progesterone/Oestrogen test.
Sample requirements: 6 x plain saliva samples and 1 x first morning urine sample (collected at timed intervals over the course of one day).
Patient requirements: Certain drugs including SSRI’s, benzodiazepines, NSAID’s, anti-hypertensives, beta-blockers, adrenergics, calcium channel blockers and steroids (including hormones, inhalers and creams) may influence the results and should be avoided 48 hours prior to the test. The use of the contraceptive pill, natural progesterone or HRT can influence the results, and should be avoided prior to testing unless wishing to monitor therapy. If monitoring therapy specimen should be obtained approximately 8-10 hours AFTER the last dose of oral, transdermal, or vaginal hormone-containing medication.
Analytes measured: Cortisol, DHEA, Melatonin, Progesterone, Oestrogen, Progesterone/ Oestrogen Ratio, Testosterone, 2-Hydroxyoestrogen, 16-Alpha-Hydroxyoestrone plus ration between the two, Creatinine
Product Code: END14